Essential medication tapering guide before ibogaine treatment

One of the most critical aspects of preparing for ibogaine treatment is properly tapering off certain medications. This is not optional — some drug interactions with ibogaine can be life-threatening. **Medications that MUST be stopped (with medical supervision):** 1. **SSRIs** (Prozac, Zoloft, Lexapro, etc.) — Taper over 2-6 weeks depending on the specific SSRI. Fluoxetine (Prozac) requires the longest washout due to its long half-life. 2. **Methadone** — Must taper to ≤30mg/day minimum. Many clinics prefer ≤20mg. This process takes 4-12 weeks. 3. **Benzodiazepines** — Taper gradually under medical supervision. Abrupt cessation can cause seizures. 4. **Tramadol** — Lowers seizure threshold. Must be fully cleared. 5. **Any QT-prolonging medications** — Check with your provider. **Medications generally safe to continue:** - Blood pressure medications (most) - Thyroid medications - Non-SSRI supplements **Important notes:** - ALWAYS work with your prescribing doctor AND your ibogaine provider - Never taper medications on your own - Get a comprehensive EKG before treatment - Be honest about everything you're taking, including supplements This is not medical advice — consult with your treatment team for personalized guidance.